IISPPR

Category: Health

Health
Rajat Rao

Impact of Social Isolation on Elderly People

Social isolation in elderly individuals, particularly women aged 60-69, is linked to health issues such as depression, cardiovascular disease, and dementia. Factors like hearing loss, loss of a spouse, and low social engagement contribute to isolation. The COVID-19 pandemic worsened loneliness due to financial concerns and lack of digital connectivity. Those with lower education levels or divorced individuals are especially vulnerable. Research highlights that social connectedness improves well-being and longevity. Initiatives like community outreach, telehealth services, and digital literacy programs can help mitigate the impact of isolation, fostering stronger social ties and enhancing quality of life for older adults.

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Health
Palak Kuraichya

Portrait of a serial killer

The “Portrait of a Serial Killer” takes you inside the twisted minds of those who kill repeatedly. It uncovers how childhood trauma, emotional neglect, antisocial personality disorder and other deep psychological disorders shape their need for power and control. From their cold detachment to the dark fantasies that fuel their actions, the post explores the chilling traits and motivations behind these killers. With a focus on the haunting impact on victims and society, it offers a gripping, humanized look into the forces that drive someone to commit the unthinkable.

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Health
Mureithi Melvin

HEALTH REVIEW.

By Mureithi Melvin

Worth Noting:

Counseling, especially in today’s context, requires constant professional development and emotional investment. The mental and emotional toll it takes on practitioners is immense, yet they are often expected to provide their services without guaranteed financial support. This leaves them vulnerable to exploitation, which can further undermine the quality of services offered to those in need.
There is a pressing need for counselors to be enrolled in permanent and pensionable roles. A system that provides long-term employment opportunities would not only safeguard the well-being of counselors but also enhance the quality of care they provide. A permanent position allows for job security, benefits such as healthcare, and the peace of mind to focus on helping others without the constant fear of financial instability.
Pro bono services, while a noble undertaking, have long been the norm in the counseling profession. Many counselors, particularly those at the grassroots level, offer their expertise for free, driven by a passion to help individuals navigate life’s challenges. However, the practice of offering such services without financial compensation has serious implications, not only for the well-being of the counselors but also for the broader system of governance.

The Strain of Unpaid Work

While pro bono counseling offers critical support to marginalized and underserved communities, it places a significant strain on counselors who, more often than not, are working without the financial stability that paid employment offers. These professionals are highly trained and possess extensive qualifications, including a Bachelor of Arts in Counseling Psychology, but many still struggle to make a living through their work. The reality is that without financial compensation, counselors are often left to work in challenging conditions with little to no support, leading to burnout and high turnover rates within the field.

Counseling, especially in today’s context, requires constant professional development and emotional investment. The mental and emotional toll it takes on practitioners is immense, yet they are often expected to provide their services without guaranteed financial support. This leaves them vulnerable to exploitation, which can further undermine the quality of services offered to those in need.

The Call for Permanent and Pensionable Positions

There is a pressing need for counselors to be enrolled in permanent and pensionable roles. A system that provides long-term employment opportunities would not only safeguard the well-being of counselors but also enhance the quality of care they provide. A permanent position allows for job security, benefits such as healthcare, and the peace of mind to focus on helping others without the constant fear of financial instability.

Furthermore, pensionable employment would allow counselors to plan for their futures, as it ensures that they will be supported in their later years. The lack of such provisions often means that, after years of service, counselors are left without a safety net, making it difficult for them to retire with dignity. This is especially concerning when considering the emotional labor involved in the counseling profession.

Impact on Governance

The systemic integration of counselors into permanent and pensionable positions would have a profound impact on governance. By recognizing counselors as essential members of the workforce and providing them with stable employment, we are investing in the long-term mental and emotional health of our society. The counseling profession plays a critical role in addressing mental health issues, preventing crime, and fostering social cohesion. By ensuring that counselors are properly compensated, we acknowledge their value and prioritize mental health at the governance level.

In turn, when counselors are financially secure, they can better contribute to policy development and advocacy. Their experience and expertise become invaluable in shaping mental health frameworks, supporting vulnerable populations, and developing educational programs to prevent mental health crises. This strengthens the overall governance structure, as the well-being of citizens directly affects the stability and progress of any nation.

Conclusion

The time has come to move beyond the pro bono model for counselors and recognize their vital contribution to society. By providing permanent, pensionable employment, we are not only investing in the future of counselors but also in the future of our communities and governance structures. As a society, we must advocate for the fair treatment of mental health professionals, ensuring they are adequately compensated for their work. By doing so, we enhance not only their professional satisfaction but also the overall quality of life for the individuals and communities they serve. It’s time to give counselors the support they deserve, creating a sustainable and impactful mental health infrastructure for generations to come.

Prepared by, Mureithi Melvin, BA (Couns. Psych.) Ongoing- KCA, Dip. (Couns. Psych.), Hons. Doc. (Trg.) – Ulumudin Markaz, Assoc. Psych. (KCPA), Mental Health Advocate, ISSUP Member.

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Health
ketaki baravkar

MAOA and CDH13: An Overview of Gene Anatomy, Structural Variations, and Behavioral Implications

The MAOA and CDH13 genes play crucial roles in neurobiology, influencing neurotransmitter metabolism and neuronal connectivity. Variants in these genes are linked to aggression, impulsivity, and psychiatric disorders. While research supports these associations, gaps remain in understanding gene-environment interactions, ethnic variations, and precise molecular mechanisms affecting behavior and mental health.

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Health
Niharika Punia

HOW CHILDHOOD TRAUMA INFLUENCES SPIRITUAL AWAKENING, ETHICAL REASONING, AND HEALING

Childhood trauma profoundly shapes spiritual beliefs, moral reasoning, and healing paths. Many survivors experience spiritual awakening, explore mysticism, or shift their ethical perspectives to find meaning. Understanding these transformations helps in developing holistic trauma recovery approaches, fostering post-traumatic growth, resilience, and deeper existential awareness in survivors’ healing journeys.

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Health
khushi Jain

The Impact of Sleep Deprivation on Cognitive Function and Daily Life

Khushi Jain , Bhumi Sharma  ‘Sleep Deprivation’ or Insufficient sleep to meet an individual’s physiological and psychological needs is getting more common day by day due to lifestyle changes, work schedules and even health-related concerns. Many people, motivated by the need to be the best , prioritize their work, social meetings and activities, or even their screen time over sleep, leading to a delay in melatonin production which in turn disrupts their biological clock and sleep-wake cycles. Without proper sleep, individuals can show a significant decline in various areas of cognitive abilities like alertness, vigilance, attention and concentration. Evidence also suggests that sleep deprivation can also affect higher order cognitive processes, such as problem solving and decision making, as many of these higher order capabilities are believed to be moderated by the prefrontal cortex, which is supposed to be affected by prolonged sleep disturbance.   The Link Between Repetitive Negative Thinking and Sleep Disturbances Consistent with prominent theories of psychopathology, research has reliably shown repetitive negative thinking (RNT) to be a central characteristic of many psychiatric conditions (Beck & Clark, 1988; Borkovec, Alcaine, & Behar, 2004; Rachman, 1997)(Stewart et al., 2018). RNT can manifest in many ways including worry, rumination, and obsessing, but has the shared feature that it is exhibited as frequent negative thoughts that are difficult to control (Ehring & Watkins, 2008). In addition to being characterized by elevated RNT, many psychiatric disorders are also characterized by disruptions in the duration and timing of sleep (Apa, 2013; Boivin, 2000; Harvey, 2008, 2011; Wulff, Gatti, Wettstein, & Foster, 2010)(Stewart et al., 2018). Harvey, Murray, Chandler, and Soehner (2011) argue that sleep disturbance should be viewed as a transdiagnostic process, as it is a feature of most psychiatric conditions. For example, sleep disruptions are reported by up to 90% of those experiencing an acute depressive episode (Wulff et al., 2010) (Stewart et al., 2018).  A number of studies document a relationship between Repetitive Negative Thinking (RNT) and reductions in sleep duration or quality (Fairholme et al. 2013; Guastella and Moulds 2007; Harvey 2002; Thomsen et al. 2003; Zoccola et al. 2009) (Nota & Coles, 2014). For example, sleep deprivation has been linked to increased rumination and decreased mood (Baglioni et al. 2010; Pilcher and Huffcutt 1996; Walker 2009) (Nota & Coles, 2014). However, there is still more to be learned about the relation between RNT and sleep duration. Experimental studies that induce rumination or worry prior to sleep have been shown to reduce sleep quality (Gross and Borkovec 1982; Vandekerckhove et al. 2012) and naturally occurring levels of RNT have been shown to prospectively predict sleep quality (Takano et al. 2012) (Nota & Coles, 2014).  The Link Between Social Isolation, Loneliness, and Sleep Disturbances A large number of older people encounter both objective and subjective types of social isolation and sleep disorders. Social isolation increases a person’s risk of a wide range of adverse health outcomes and premature death. Social isolation can cause poor sleep quality that has been proposed as one of the possible mechanisms by which social isolation affects people’s health and quality of life. (Azizi-Zeinalhajlou et al., 2022)  Another similar factor is loneliness, which can be defined as the feeling of being separate from others, and has been identified as one key aspect of social factors that influence health (Cacioppo and Hawkley (2003) proposed that sleep disturbance is a mechanism through which loneliness influences health, citing two studies led by (Cacioppo (2002a, 2002b) in which lonely persons reported lower sleep quality and showed lower sleep efficiency and higher levels of wake time after sleep onset than non-lonely persons. Therefore, it is essential to comprehend these issues and address them through various treatment plans. The Impact of Sleep Deprivation on Psychological Functioning Sleep deprivation or insufficient sleep is very intricately connected to negative thinking. As we know, lack of rest and proper sleep makes the brain more volatile and more susceptible to emotional reactions and distressing thoughts and feelings. When the brain does not get enough sleep, the prefrontal cortex, which oversees rational thinking, weakens, whereas the amygdala, responsible for processing emotions, becomes increasingly reactive. These imbalances cause a lot of irregularities in an individual, such as frequent mood swings, increasing anxiety as well as ruminating or over-fixating on a problem. Chronic sleep deprivation plays a role in escalating mild symptoms of disorders like anxiety and depression but it also majorly increases the risk of developing serious mental health conditions and disorders. Prolonged sleep deprivation disrupts the brain’s neural pathways, especially those involved in emotional regulation and stress response, which reduces the brain’s ability to recover from emotional strain and cope with daily stressors. Over time, this disruption can have lasting psychological effects, as the brain’s resilience against stress weakens, making it more susceptible to mood disturbances and mental health disorders (Jansen & Narayan, 2024).  There is sufficient evidence to show the relationship between sleep disturbance and negative thinking. Sleep is an important factor to consider in developmental psychopathology (Meltzer, 2016). In adults, higher levels of RNT are associated with longer sleep onset latency and poorer sleep quality (Guastella & Moulds, 2007; Nota & Coles, 2015; Zoccola, Dickerson, & Lam, 2009). Further, an initial study in adults that incorporated both sleep duration and sleep timing components in one study found that sleep timing uniquely impacted RNT. Specifically, delayed sleep timing was associated with higher levels of RNT (Nota & Coles, 2015). This can have a serious effect on a person’s mental, emotional and physical well-being. Studies have shown that prolonged insufficient sleep can reduce the size of the hippocampus, which deals with memory and emotional regulation, making one more susceptible towards mental health conditions like anxiety and depression. Due to sleep deprivation, the brain loses its ability to regulate emotions and process information which leads to heightened stress responses and difficulty in concentrating. It can also tamper with the production of neurotransmitters like serotonin and dopamine, which plays an important role in stabilizing mood. This can cause

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Health
Ayush Burnwal

THE IMPACT OF COVID-19 ON HEALTHCARE INEQUITIES:- Assessing the long-term Economic consequences on Vulnerable Population

 HEALTHCARE ECONOMICS  THE IMPACT OF COVID-19 ON HEALTHCARE INEQUITIES:- Assessing the long-term Economic consequences on Vulnerable Population   By:- Sheetal  Ayush Burnwal Zaheen Qureshi Sanjula D Pankhudi Jha             INTRODUCTION The first whispers about an obscure virus were heard in Wuhan, China. A few months later, it began to spread, accompanying the number of cases contaminated rising swiftly and comprehensively in domains of the world for fear that on March 11, 2020, the WHO regularly announced the new affliction as a worldwide universal. The disease has a development ending from two to fourteen days but generally remains asymptomatic. If indicative, the universal signs and symptoms noticed include turmoil, dry cough, shortness of whiff, proneness, neck sensitivity, restlessness, and in harsh cases leads to severe respiratory distress syndrome and pneumonia that in decay can finish in multiple means of loss and certainly death. The harsh performance of affliction was majorly seen in toddlers and aging old people. Many measures were taken to stop the affliction i.e. seclusion, quarantine of distrust, tight infection administration conduct, contact security measures, and social passing.  In reference to this healthcare inequities may be delimited as differences in healthcare rank or the disposal of well-being resources between various populace groups, arising from public environments at which point people are innate, evolve, live, work, and age. Health inequities are prejudiced and could be weakened for one right join of government tactics. A big culture, variations in possessions across domains, and a feeble community health system in India formal a challenge in conditions of momentary and preparedness to handle a quickening caseload.16 In conditions of available capital, from the 3.6% GDP expense in healthcare, only 1.5% is apiece Government, and households carry more than 2%, that is to say, 65% of payment is out of pocket.12 The system working, when COVID hit, was accordingly underprepared to deal with this crisis. The risk of harsh complexities from COVID-19 is higher for certain unsafe people, particularly the ones who are retired, frail, or have diversified never-ending environments. The other susceptible group is made apiece stranded, weak, regular traders as the ever-growing strength cost keeps aggressive those just above the poverty line back into want. Vulnerable societies were individual big groups in India, labeled all along COVID. OBJECTIVE  To examine healthcare inequities from a multidimensional lens of economics, in the aftermath of COVID-19.      HEALTHCARE INEQUITIES India however confronts many difficulties in providing equitable healthcare to all due to its large population. Healthcare inequities are influenced by a number of factors such as socioeconomic status, regional differences, inadequate healthcare facilities, gender stereotypes, etc. These inequities produce systematic disadvantages and cause disparities among different sections of the population.   The rural population often prefers public health because it provides them with the most accessible and affordable healthcare option, as they typically lack the financial means to access private healthcare services, which are often more expensive and may not be readily available in their communities. It is, therefore, the public health system that serves the majority of India’s vulnerable rural population. Nearly 75 percent of health-related infrastructure, medical workforce, and other health resources are concentrated in urban areas, where only 27 percent of the population resides. This leaves the poorest segments of the population in rural areas facing numerous access barriers.    Providing well-equipped public healthcare becomes quintessential in reducing inequities between the rural and the urban. It is therefore important to have a strong and effective public healthcare system as the rural population’s access to basic health services is mainly through primary healthcare centers which is widely regarded as the most inclusive, equitable, and cost-effective way to achieve universal health coverage. PHCs in India are understaffed as more than 37% of the health assistant positions, 34% of laboratory staff and 21% of nurse positions are vacant. There is widespread absenteeism among healthcare workers in PHCs. Due to poor management and ill-equipped services provided by PHCs, the rural population is forced to seek services from the private sector, causing more financial complications and widening the rural-urban gap.   One of the main challenges is that health spending in India is mostly out-of-pocket. OOP health expenditure imposes an extreme financial burden on households because the fees and cost of treatment are very high in private facilities and unaffordable for people earning low incomes. OOP expenditure on health is one of the biggest reasons for people falling into poverty in India.   Nearly 70% of hospitals and 40% of hospital beds are private. Health insurance is largely private, and the urban poor cannot afford private care. The Indian healthcare budget is inadequate; the total healthcare expenditure was at only 1.3% of gross domestic product in 2021, which is the lowest in the BRICS group. There is a disparity in the availability of infrastructure and resources between rural and urban areas in India. Evidence points out that among all health workers, 67% were serving in urban areas where 33% of the population is based; and 33% were serving in rural areas where 67% of the population resides. India has approximately 860 beds/million population as compared to WHO’s estimate of the world average, which is 3,960 beds/million population, proving that our healthcare infrastructure is seriously lacking.    Gender stereotypes and inequalities can also impact access to healthcare, particularly for women. Cultural norms may limit women’s autonomy in making health decisions, leading to delays in seeking care or requiring approval from male family members. Additionally, gender-based discrimination and violence can further hinder women’s access to medical services. Women and elderly patients often rely on family support to reach healthcare facilities and may need permission before spending money on treatment, taking tests, or attending follow-up appointments.   India is a major hub for private health tourism. Private hospitals in India are seeing an influx of patients. India ranks among the top 20 countries in terms of private expenditure on health in percent GDP terms – around 4.5-5 percent of GDP. The extra revenue

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Health
Eesha Madan

Attention deficit hyperactivity disorder (ADHD)

Attention deficit hyperactivity disorder (ADHD) by Eesha Madan 1) Abstract Attention-deficit/hyperactivity disorder (ADHD) is one of the most common childhood neurodevelopmental disorders that impacts the parts of the brain that help us plan, focus on, and execute tasks. ADHD symptoms vary by sub-type — inattentive, hyperactive, or combined — and are often more difficult to diagnose in girls and adults. Here, we review the symptoms, causes, types, and treatments associated with ADHD.  2) Understanding Attention-deficit/hyperactivity  disorder: ADHD, attention deficit hyperactivity disorder, is a developmental condition of inattention and distractibility, with or without accompanying hyperactivity. It is one of the most common neurodevelopmental disorders affecting children. The signs of ADHD start early in childhood. But some people don’t find out they have it until they are older. Individuals suffering from this disorder show patterns of developmentally inappropriate levels of inattentiveness, hyperactivity, or impulsivity. Scientists have discovered there are differences in the brains, nerve networks and neurotransmitters of people with ADHD. It can limit a person’s ability to study or work, and it can lead to stress, anxiety, and depression. This disorder includes Autism Spectrum, Intellectual Disability and Specific Learning Disorders. These disorders if not attended to can lead to more serious and chronic disorders in adulthood.  An article published in “India Today” mentioned that it is estimated that 10 million Indian children are diagnosed with ADHD annually.    3) Signs of ADHD All kids struggle at times to pay attention, listen and follow directions, sit still, or wait their turn. But for kids with ADHD, the struggles are harder and happen more often. Kids with ADHD can show signs in different areas. They might be: Inattentive: Kids who are inattentive (easily distracted) have trouble focusing their attention, concentrating, and staying on task. They may not listen well to directions, may miss important details, and may not finish what they start. They may daydream or dawdle too much. They may seem absent-minded or forgetful and may lose track of their things. Hyperactive: Hyperactive Kids are fidgety, restless, and easily bored. They may have trouble sitting still, or staying quiet when needed. They may rush through things and make careless mistakes. They may climb, jump, or roughhouse when they shouldn’t. Without meaning to, they may act in ways that disrupt others. Impulsive: Kids who are impulsive act too quickly before thinking. They often interrupt, might push or grab, and find it hard to wait. They may do things without asking for permission, take things that aren’t theirs, or act in ways that are risky. They may have emotional reactions that seem too intense for the situation. Sometimes parents and teachers notice signs of ADHD when a child is very young. But it’s normal for little kids to be distracted, restless, impatient, or impulsive — these things don’t always mean that a child has ADHD. Attention, activity, and self-control develop little by little, as children grow. Kids learn these skills with help from parents and teachers. But some kids don’t get much better at paying attention, settling down, listening, or waiting. When these things continue and begin to cause problems at school, home, and with friends, it may be ADHD. Some people with ADHD have fewer symptoms as they age, but some adults continue to have major symptoms that interfere with daily functioning. In adults, the main features of ADHD may include difficulty paying attention, impulsiveness and restlessness. Symptoms can range from mild to severe. Many adults with ADHD aren’t aware they have it — they just know that everyday tasks can be a challenge. Adults with ADHD may find it difficult to focus and prioritize, leading to missed deadlines and forgotten meetings or social plans. The inability to control impulses can range from impatience waiting in line or driving in traffic to mood swings and outbursts of anger. Adult ADHD symptoms may include: Impulsiveness Disorganization and problems prioritizing Poor time management skills Problems focusing on a task Trouble multitasking Excessive activity or restlessness Poor planning Low frustration tolerance Frequent mood swings Problems following through and completing tasks Hot temper Trouble coping with stress 4) What causes ADHD? Despite how common ADHD is, doctors and researchers still are not sure what causes the condition. The exact cause of ADHD is unknown, but the condition has been shown to run in families. While there is growing evidence that genetics contribute to ADHD and several genes have been linked to the disorder, no specific gene or gene combination has been identified as the cause of the disorder. However, some research suggests that the following factors may play a role in developing ADHD: Genetics: Around 3 out of 4 children with ADHD have a relative with the condition. Premature birth: Infants born even 1 month prematurely may face an increased risk of developing ADHD. Low birth weight: Results of one meta-analysisTrusted Source suggest a small but significant link between low birth weight and the development of ADHD. Stress and other lifestyle factors during pregnancy: Findings of a study from 2012 support a previously established connection between maternal stress during pregnancy and the development of ADHD. The authors of this study conclude that smoking tobacco and drinking alcohol during pregnancy may also increase the child’s risk of developing the disorder. Traumatic brain injury: In 2015, researchers found a possible linkTrusted Source between mild traumatic brain injury and ADHD in student athletes. However, the causal relationship was unclear. ADHD is not caused by too much screen time, poor parenting, or eating too much sugar. 5) Types of ADHD: According to DSM-5, the 3 types of attention-deficit/hyperactivity disorder (ADHD) are (1) predominantly inattentive, (2) predominantly hyperactive/impulsive, and (3) combined. The specific criteria for attention-deficit/hyperactivity disorder are as follows: 5.1 Inattentive:    This must include at least 6 of the following symptoms of inattention that must have persisted for at least 6 months to a degree that is maladaptive and inconsistent with developmental level: Often fails to give close attention to details or makes careless mistakes in schoolwork, work, or

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Health
Bhavya Gupta

Impact of Social Connections in Old Age

Impact of Social Connections in Old Age  By Bhavya Gupta  Introduction Social connections are an integral part of individuals’ mental and emotional well-being throughout their lives, especially in their later years. Social connectedness means a temporary feeling of belonging together with others. It can be defined in terms of inclusiveness, satisfaction with one’s social situation, and degree of saliency of ties, without necessarily requiring immediate contact. It translates social experiences arising from recent interactions with and the consciousness of others (Van Bel et.al., 2009). Good numbers of social relations have been reported to reduce depression and anxiety in geriatric populations (Scazufca & Seward, 2024). Old age is connected with a variety of psychosocial problems- loneliness, depression, and deterioration of cognitive functions among others In older adults, it has been established that social interaction and the frequency of socialization are correlated with decreased risk of cognitive failure and dementia (Mahalingam et al., 2023). For elderly people, one-fourth experience loneliness, which increases their vulnerability to various mental health problems (Scazufca & Seward, 2024). Further research also points out that even low levels of social interaction result in fewer depressive symptoms (Lee et al., 2024). Social isolation has been conceptualized as a risk factor for Alzheimer’s disease and related dementias (Joshi et al., 2023). Psychological Landscape of Old Age In general, the psychological terrain of old age is burdened with complex mental health issues, arising from social isolation and loneliness. Literature shows that over half of older persons report suffering from social isolation, and a significant number estimated one-third-suffer severe loneliness, thus leading to further risks of mental health disorders such as depression and cognitive decline (Sivakumar et al., 2024; Puglia, 2022). Common Mental Health Challenges Depression and Anxiety: Depression during the old age stage is very common, which often roots into such emotional substructures as loss, diminished mobility, or the lessened sense of self-worth that accompanies retirement (Bryant, 2010). Depression in old age is also associated with cognitive impairment and contributes to a heightened risk for suicidal ideation and behaviours among older persons (Puglia, 2022). Cognitive Decline: Even though older adults remain dementia-free for their lifetime, there comes cognitive decline and neurodegenerative alteration with this advancing age, which suggests shared pathophysiological mechanisms (Gonzales et.al., 2019). According to these studies, it is noted that loneliness impacts mental well-being like what physical deteriorations do by worsening cognitive problems, as well as in conjunction with increased risk for Alzheimer’s disease and other dementias (Kim & Chey, 2023). Dementia and Behavioral Symptoms: Behavioral symptoms including agitation, confusion, and aggression are common in some cases of dementia in the elderly, which puts demand on family relationships and increases the burden of formal caregivers. Under such strain, many families consider alternatives, opting for institutionalisation, since few caregivers can meet the high needs of their loved ones at home (Puglia, 2022). Contributing Factors Physical health: It has been observed that greater experiences of adversities over a lifetime impair physical health (Levinsky & Schiff, 2021). These often present chronic health conditions leading to a reduction in social interactions (Sivakumar et al., 2024). Retirement: Different types of social disconnection that cause much loneliness may surface as a result of the transition from working life to retirement (Kim & Chey, 2023). Life transitions: Emotional health can be seriously affected by phase transitions such as the death of loved ones or bereavement (“The Landscape of Loneliness,” 2022). Despite these common challenges in the ageing population, an impressive number of aged people display resilience and adaptiveness towards the ageing process. Research suggests that strong community support, family involvement, and opportunities for meaningful social interaction form a trinity to cushion these people from mental health-related challenges. Such an atmosphere that favours social engagement is critical in enhancing sound mental health and preventing experiences of loneliness among the elderly, culminating in improved quality of life. Social connection is eminent in ensuring good mental health, particularly in older adults. Valuable social networks can reduce loneliness, increase much-needed emotional support, and foster stimulating cognitive engagements that, in turn, lower the risk of developing severe cognitive decline. Such studies show that frequent social engagements grant them better emotional well-being; older adults with strong social networks are less likely to suffer from depression and anxiety (Awad et al., 2024; Scazufca & Seward, 2024). The Reduction of Loneliness and Isolation One of the salient dividends of social connections is bringing about a sense of well-being in older adults combating loneliness, which has been acknowledged as a significant problem in over 50% of older adults (Sivakumar et al., 2024). Loneliness in advanced years has seen its negative impact in causing emotional distress, and social engagement is an available remedy. Joining community activities such as clubs, going to senior centres, and group parties fosters a sense of belonging and agency, strengthening one’s identity and connection with others. Emotional Support Emotional support can be defined as care, concern, empathy, reassurance, comfort, and acceptance expressed through verbal or nonverbal means. Emotional support is quite important in self-help groups wherein members share support, and it is equally valuable in attachment relationships, wherein caregivers provide emotional support to children (American Psychological Association, 2018). This support reduces hopelessness and therefore lessens stress levels, which could otherwise be problematic for the affected aged persons dealing with their health issues, grief, or changing life transitions (Awad et al., 2024). Such emotional bonds offered to persons become shields when the mental scape is attacked or in poor condition and serve right that which had developed resilience among older adults, thus enabling them to cope better with life problems and maintain a feeling of positivity. There is ample vent for thinking that emotional support offers significant protection from cognitive decline, but the neural mechanisms that may or may not involve this support in such cognitive functions remain at best unclear (Kim et.al., 2019). Engagement for Cognitive Cliff: Development of Cognitive Abilities Frequent social interactions also continue to yield effectual support on cognitive health. Studies have shown that engaging socially stimulates cognitive

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Health
Palak Parashar

Efficacy of pharmacological interventions in schizophrenia treatment Research

by Palak Parashar, Humaira Hasan, Upasana Koul Introduction Schizophrenia is a serious brain disorder affecting around 1% of the global population and is one of the top 10 causes of disability worldwide (Marder & Cannon, 2019). This condition is characterized by symptoms such as hallucinations (e.g., seeing or hearing things that aren’t there), delusions (false beliefs), disorganized speech, and abnormal behavior. Additionally, individuals with schizophrenia often experience a lack of motivation, reduced emotional expression, and cognitive difficulties, including problems with thinking, memory, and decision-making (Jauhar, Johnstone, & McKenna, 2022). The impact on daily life can be significant, leading to severe disability and incomplete recovery. Even individuals who show improvement may still struggle with social isolation, stigma, and limited opportunities for building close relationships. Unemployment rates are high among those with schizophrenia, and lifestyle factors such as poor diet, weight gain, smoking, and substance use contribute to a reduced life expectancy of 13 to 15 years (Hjorthøj, Stürup, McGrath, & Nordentoft, 2017; Kahn, 2020). The lifetime risk of death by suicide for individuals with schizophrenia ranges from 5% to 10% (McCutcheon, Reis Marques, & Howes, 2020).   Current diagnosis and treatment primarily target psychotic symptoms, but negative and cognitive symptoms are equally important due to their significant impact on social and professional functioning. These symptoms often do not respond well to conventional antipsychotic medications (Kahn, 2020; Jauhar, Johnstone, & McKenna, 2022). Historically, schizophrenia was conceptualized by Emil Kraepelin as “dementia praecox,” a term later renamed “schizophrenia” by Eugen Bleuler. Notably, both Kraepelin and Bleuler did not consider positive symptoms like delusions and hallucinations as the primary characteristics of the disorder. This historical perspective supports the view that a more comprehensive approach is needed for understanding and treating schizophrenia (Kahn, 2020).   Schizophrenia diagnosis involves a detailed psychiatric history and mental status examination, ruling out other potential medical and psychiatric causes of psychosis. Risk factors for developing schizophrenia include birth complications, being born in a specific season, maternal malnutrition, maternal influenza during pregnancy, a family history of the disorder, childhood trauma, social isolation, cannabis use, minority ethnicity, and living in urban environments (Messias, Chen, & Eaton, 2007; Davis et al., 2016). The exact cause and biological mechanisms of schizophrenia remain unclear due to its complexity and variability. Despite being relatively uncommon, schizophrenia has a significant impact on the global burden of disease, with more than half of those diagnosed experiencing multiple coexisting psychiatric and medical conditions (Chong et al., 2016).    The pharmacological treatment for  schizophrenia:- Pharmacological treatment for schizophrenia primarily involves antipsychotic medications, which are categorized into two groups:- 1.First-generation antipsychotics (FGAs) 2.Second-generation antipsychotics (SGAs)  1)First-generation antipsychotics, also known as typical antipsychotics, are dopamine receptor antagonists (DRA). These include: Phenothiazines, trifluoperazine, perphenazine, prochlorperazine, acetophenazine, triflupromazine, mesoridazine Butyrophenones: haloperidol Thioxanthenes: thiothixene, chlorprothixene Dibenzoazepines: loxapine Dihydroindoles: molindone Diphenylbutylpiperidines: pimozide. (Drummond N, McCleary L, Freiheit E, Molnar F, Dalziel W, Cohen C, Turner D, Miyagishima R, Silvius J.  2018 Jennings AA, Guerin N, Foley T.  Faden J, Citrome L.  Pharmacother. 2019) .    2. Second-generation antipsychotics, also known as atypical antipsychotics, are serotonindopamine antagonists. As of 2016, the Food and Drug Administration (FDA) has approved 12 atypical antipsychotics. These are: Risperidone Quetiapine Aripiprazole Asenapine Lurasidone Iloperidone Brexpiprazole Clozapine ( Haddad PM, Correll CU.  Nov 2018) .   What is Schizophrenia? Schizophrenia may be defined as an acute mental illness that is characterized by disturbance in cognition( illogical thinking), behavior, speech, and hallucinations(hearing voices, seeing things that aren’t present) or delusions. (American Psychological Association, n.d.) The DSM-5, or the Diagnostic and Statistical Manual of Mental Disorders, describes the symptoms of schizophrenia as including disorganized speech (e.g., frequent derailment or incoherence), delusions, hallucinations, or catatonic behavior. (NCBI, n.d., Table 22)   Prevalence and Onset: Schizophrenia is a genetic neurocognitive disorder that affects approximately 1% of the population, typically appearing between the ages of 21 and 25 in males and 25 and 30 in females. (Zhan et al., 2023) Extensive research suggests that from 1990 to 2019, global schizophrenia cases rose by over 65%, new diagnoses by 37%, and health impacts (DALYs) by 65%, while age-adjusted rates stayed stable. (Solmi et al., 2023) Treatment: Schizophrenia treatment is lifelong and combines medications with psychosocial support, guided by a psychiatrist and a care team. Antipsychotic medications, including both first- and second-generation options, are the primary treatment, with long-acting injectables available for better adherence. Additional medications, such as antidepressants or mood stabilizers, may be used based on individual needs. Psychosocial approaches like therapy, social skills training, family support, and vocational rehabilitation enhance coping, communication, and daily life skills. Severe cases may require hospitalization for stabilization, while electroconvulsive therapy (ECT) is considered for those unresponsive to other treatments. With proper care, many people with schizophrenia can manage their symptoms effectively. (Mayo Clinic, n.d.)   Prescribed Drugs First-Generation Antipsychotics First-generation antipsychotics (FGAs), also known as typical antipsychotics, primarily work by blocking dopamine receptors to alleviate symptoms of various mental health conditions. These medications are commonly prescribed for issues such as acute mania, agitation, and bipolar disorder. Some examples of FGAs include Chlorpromazine (Thorazine), Fluphenazine (Prolixin), Haloperidol (Haldol), and Loxapine (Loxitane), among others. (Mayo Clinic, n.d.) Mechanism: Both first- and second-generation antipsychotics block dopamine in the ventral tegmentum to reduce positive symptoms. However, first-generation drugs also affect the nigrostriatal dopamine system, leading to extrapyramidal side effects, which second-generation drugs cause less frequently. (Grace & Uliana, 2023) Efficacy: Studies revealed minimal differences in efficacy between First Generation Antipsychotics and Second Generation Antipsychotics, but haloperidol was less effective than amisulpride and clozapine. Additionally, olanzapine showed greater improvement in functional capacity compared to quetiapine and ziprasidone. (Pike et al., 2009)   Second Generation Antipsychotics Second-generation antipsychotics (SGAs), also known as atypical antipsychotics, are newer medications that work differently from first-generation antipsychotics. Instead of fully blocking dopamine receptors, SGAs partially block them and may also influence other neurotransmitters like serotonin. Examples of SGAs include Aripiprazole (Abilify), Clozapine (Clozaril), Olanzapine (Zyprexa), Risperidone (Risperdal), and Quetiapine (Seroquel). (Mayo Clinic, n.d.)   Mechanism: These medications inhibit some serotonin and dopamine

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